3,5-diiodo-L-tyrosine

Term ID

CHEBI:15768

Synonyms

(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
3,5-Diiodo-L-tyrosine
3,5-Diiodotyrosine
diiodotyrosine
DiIY
DIT
L-3,5-diiodotyrosine
L-Diiodotyrosine

Definition

A diiodotyrosine that is L-tyrosine carrying iodo-substituents at positions C-3 and C-5 of the benzyl group. It is an intermediate in the thyroid hormone synthesis.

References

Beilstein:2218691
CAS:300-39-0
DrugBank:DB03374
Drug_Central:3146
Gmelin:1128682
HMDB:HMDB0003474
KEGG:C01060
LINCS:LSM-5697
PDBeChem:TYI
PMID:11344555
PMID:15206581
PMID:15589368
Reaxys:2218691

Ontology

ChEBI ( EBI )

Relationships

is a type of: diiodotyrosine L-tyrosine derivative non-proteinogenic L-alpha-amino acid

diiodotyrosine L-tyrosine derivative non-proteinogenic L-alpha-amino acid Show first 5 Terms
has_role: human metabolite mouse metabolite

human metabolite mouse metabolite Show first 5 Terms
inverse has_functional_parent: N-acetyl-L-phenylalanyl-L-diiodotyrosine

N-acetyl-L-phenylalanyl-L-diiodotyrosine Show first 5 Terms
inverse is_conjugate_base_of: 3,5-diiodo-L-tyrosinate(1-)

3,5-diiodo-L-tyrosinate(1-) Show first 5 Terms
inverse is_substituent_group_from: 3,5-diiodo-L-tyrosine residue

3,5-diiodo-L-tyrosine residue Show first 5 Terms
is_conjugate_acid_of: 3,5-diiodo-L-tyrosinate(1-)

3,5-diiodo-L-tyrosinate(1-) Show first 5 Terms

Phenotype

Phenotype resulting from 3,5-diiodo-L-tyrosine

Phenotype where environments contain 3,5-diiodo-L-tyrosine

Phenotype modified by environments containing 3,5-diiodo-L-tyrosine

Human Disease Model