Search Ontology:
ChEBI
taltirelin tetrahydrate
- Term ID
- CHEBI:157598
- Synonyms
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- (-)-N-[(S)-hexahydro-1-methyl- 2,6-dioxo-4-pyrimidinyl-carbonyl]-L-histidyl-L-prolinamide tetrahydrate
- Ceredist
- N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide tetrahydrate
- N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide--water (1/4)
- Definition
- A hydrate that is the tetrahydrate form of taltirelin. It activates neuronal cells by promoting the release and turnover of neurotransmitters (acetylcholine, dopamine) and its nerve growth factor-like action. The drug is approved in Japan and used to treat ataxia (daily activities such as gait, eating, and conversation) in patients suffering from spinocerebellar degeneration.
- References
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- CAS:201677-75-0
- KEGG:C13402
- KEGG:D01925
- PMID:12884823
- PMID:16368129
- PMID:22044177
- PMID:27212675
- PMID:9430092
- PMID:9430093
- PMID:9430094
- PMID:9430095
- PMID:9430096
- PMID:9430097
- PMID:9430098
- PMID:9430099
- PMID:9608876
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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Phenotype
Phenotype resulting from taltirelin tetrahydrate
Phenotype where environments contain taltirelin tetrahydrate
Phenotype modified by environments containing taltirelin tetrahydrate
Human Disease Model