leukotriene B4

Term ID

CHEBI:15647

Synonyms

(5S,12R,6Z,8E,10E,14Z)-5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid
(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyeicosa-6,8,10,14-tetraenoic acid
(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid
(S-(R*,S*-(E,Z,E,Z)))-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid
5(S),12(R)-dihydroxy-6(Z),8(E),10(E),14(Z)-eicosatetraenoic acid
5(S),12(R)-dihydroxy-6(Z),8(E),10(E),14(Z)-icosatetraenoic acid
5,12-Dihete
5,12-Hete
5S,12R-diHETE
5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
Leukotriene B4
LTB4

(all 12)

Definition

A leukotriene composed of (6Z,8E,10E,14Z)-icosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. It is a lipid mediator of inflammation that is generated from arachidonic acid via the 5-lipoxygenase pathway.

References

(all 46)

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: dihydroxy monocarboxylic acid hydroxy polyunsaturated fatty acid leukotriene long-chain fatty acid

dihydroxy monocarboxylic acid hydroxy polyunsaturated fatty acid leukotriene long-chain fatty acid Show first 5 Terms
has_functional_parent: icosa-6,8,10,14-tetraenoic acid

icosa-6,8,10,14-tetraenoic acid Show first 5 Terms
has_role: human metabolite mouse metabolite plant metabolite vasoconstrictor agent

human metabolite mouse metabolite plant metabolite vasoconstrictor agent Show first 5 Terms
inverse has_functional_parent: 10,11-dihydro-12-oxoleukotriene B4 10,11-dihydro-20,20,20-trihydroxyleukotriene B4 10,11-dihydro-20,20-dihydroxyleukotriene B4 12,20-dioxoleukotriene B4 12-dehydro-leukotriene B4 ... Show All 13 Terms

10,11-dihydro-12-oxoleukotriene B4 10,11-dihydro-20,20,20-trihydroxyleukotriene B4 10,11-dihydro-20,20-dihydroxyleukotriene B4 12,20-dioxoleukotriene B4 12-dehydro-leukotriene B4 12-oxo-20-hydroxyleukotriene B4 18-hydroxy-18-oxo-dinorleukotriene B4 18-hydroxyleukotriene B4 19-hydroxyleukotriene B4 20,20,20-trihydroxyleukotriene B4 20,20-dihydroxyleukotriene B4 20-hydroxy-20-oxoleukotriene B4 20-hydroxy-leukotriene B4 Show first 5 Terms
inverse is_conjugate_base_of: leukotriene B4(1-)

leukotriene B4(1-) Show first 5 Terms
is_conjugate_acid_of: leukotriene B4(1-)

leukotriene B4(1-) Show first 5 Terms

Phenotype

Phenotype resulting from leukotriene B4

Phenotype where environments contain leukotriene B4

Phenotype modified by environments containing leukotriene B4

Human Disease Model