leukotriene B4

Term ID

CHEBI:15647

Synonyms

• (5S,12R,6Z,8E,10E,14Z)-5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid
• (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyeicosa-6,8,10,14-tetraenoic acid
• (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid
• (S-(R*,S*-(E,Z,E,Z)))-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid
• 5(S),12(R)-dihydroxy-6(Z),8(E),10(E),14(Z)-eicosatetraenoic acid
• 5(S),12(R)-dihydroxy-6(Z),8(E),10(E),14(Z)-icosatetraenoic acid
• 5,12-Dihete
• 5,12-Hete
• 5S,12R-diHETE
• 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
• Leukotriene B4
• LTB4

Definition

A leukotriene composed of (6Z,8E,10E,14Z)-icosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. It is a lipid mediator of inflammation that is generated from arachidonic acid via the 5-lipoxygenase pathway.

References

• cas:71160-24-2
• chemspider:4444132
• drugbank:DB12961
• hmdb:HMDB0001085
• kegg.compound:C02165
• knapsack:C00053425
• lipidmaps:LMFA03020001
• pdb-ccd:LTB
• pubmed:10087000
• pubmed:10391868
• pubmed:10695938
• pubmed:11166796
• pubmed:11254552
• pubmed:12709426
• pubmed:12742837
• pubmed:12947016
• pubmed:1327049
• pubmed:1333134
• pubmed:1335872
• pubmed:1338371
• pubmed:15016629
• pubmed:15515787
• pubmed:16567388
• pubmed:1661709
• pubmed:17481557
• pubmed:17548641
• pubmed:17623009
• pubmed:1847289
• pubmed:20400503
• pubmed:20529300
• pubmed:20671299
• pubmed:23625922
• pubmed:32439596
• pubmed:32960415
• pubmed:33292560
• pubmed:33612149
• pubmed:6271967
• pubmed:7924852
• pubmed:8243477
• pubmed:8382716
• pubmed:8397308
• pubmed:9209678
• pubmed:9516893
• pubmed:9606840
• reaxys:4235309
• wikipedia.en:Leukotriene_B4

Ontology

ChEBI  ( EBI )

Resources

CTD