Search Ontology:
ChEBI
holomycin
- Term ID
- CHEBI:156451
- Synonyms
-
- 6-(acetylamino)-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one
- 6-acetamido-1,2-dithiolo[4,3-b]pyrrol-5(4H)-one
- N-(4,5-dihydro-5-oxo-1,2-dithiolo-[4,3-b]pyrrol-6-yl)acetamide
- N-(5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide
- N-(5-oxo-4H-dithiolo[4,3-b]pyrrol-6-yl)acetamide
- N-demethylthiolutin
- N-{5-oxo-4H,5H-[1,2]dithiolo[4,3-b]pyrrol-6-yl}acetamide
- Definition
- A dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 5 and 6 have been replaced by oxo and acetamido groups, respectively. It is an inhibitor of DNA-dependent RNA polymerase, and exhibits antibacterial and antitumour properties.
- References
-
- CAS:488-04-0
- MetaCyc:CPD-17940
- PMID:11158751
- PMID:12426344
- PMID:16890414
- PMID:17606690
- PMID:21041678
- PMID:21339958
- PMID:21342467
- PMID:21504228
- PMID:22344669
- PMID:23097183
- PMID:23147422
- PMID:23572522
- PMID:24141227
- PMID:24323287
- PMID:27018252
- PMID:28209778
- PMID:28627048
- PMID:28740758
- PMID:30194098
- PMID:32642829
- PMID:468729
- PMID:863793
- PMID:894386
- Reaxys:188430
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
- inverse has_functional_parent
-
Show first 5 Terms
Show All 6 Terms
Phenotype
Phenotype resulting from holomycin
Phenotype where environments contain holomycin
Phenotype modified by environments containing holomycin
Human Disease Model