coenzyme A

Term ID

CHEBI:15346

Synonyms

3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate}
3'-phosphoadenosine-(5')diphospho(4')pantatheine
[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate
CoA
CoA-SH
CoASH
Coenzym A
Coenzyme A
HSCoA
Koenzym A

Definition

A thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit.

References

Beilstein:77809
CAS:85-61-0
DrugBank:DB01992
KEGG:C00010
KNApSAcK:C00007258
PDBeChem:COA
PDBeChem:COZ
PMID:11923312
PMID:13025483
PMID:15014152
PMID:15893380
PMID:18407920
PMID:19666462
PMID:20351285
PMID:2981478
PMID:7310833
Wikipedia:Coenzyme_A

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: adenosine 3',5'-bisphosphate

adenosine 3',5'-bisphosphate Show first 5 Terms
has_functional_parent: ADP

ADP Show first 5 Terms
has_role: coenzyme Escherichia coli metabolite mouse metabolite

coenzyme Escherichia coli metabolite mouse metabolite Show first 5 Terms
inverse has_functional_parent: (1-hydroxycyclohexyl)acetyl-CoA (2,3,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA (2-trans,6-cis)-dodeca-2,6-dienoyl-CoA (2E,4Z)-deca-2,4-dienoyl-CoA (3S)-citryl-CoA ... Show All 93 Terms

(1-hydroxycyclohexyl)acetyl-CoA (2,3,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA (2-trans,6-cis)-dodeca-2,6-dienoyl-CoA (2E,4Z)-deca-2,4-dienoyl-CoA (3S)-citryl-CoA (3Z,6Z)-dodecadienoyl-CoA (E)-4-(trimethylammonio)but-2-enoyl-CoA (E,E)-piperonyl-CoA (R)-methylmalonyl-CoA (R)-phenyllactoyl-CoA (S)-3-hydroxyhexanoyl-CoA (S)-methylmalonyl-CoA 2'-(5''-phosphoribosyl)-3'-dephospho-CoA 2'-(5-triphosphoribosyl)-3'-dephospho-CoA 2-amino-5-oxocyclohex-1-enecarbonyl-CoA 2-benzylsuccinyl-CoA 2-furoyl-CoA 2-methylbutanoyl-CoA 3'-dephospho-CoA 3,4,4-trimethylhepta-2,5-dienoyl-CoA 3,4-dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA 3-hydroxy-3-methylbutyl-CoA 3-isopropenylpimeloyl-CoA 3-methylbut-3-enoyl-CoA 3-oxooctadecanoyl-CoA 4,8,12-trimethyltridecanoyl-CoA 5-hydroxythiophene-2-carbonyl-CoA 6-hydroxycyclohex-1-ene-1-carbonyl-CoA 6-hydroxyhex-3-enoyl-CoA 6-oxocyclohex-1-ene-1-carbonyl-CoA acetyl-CoA acryloyl-CoA acyl-CoA alk-2-enoyl-CoA but-2-enoyl-CoA butyryl-CoA cinnamoyl-CoA cis-dodec-3-enoyl-CoA cis-geranoyl-CoA cis-tetradec-3-enoyl-CoA cis-tetradec-11-enoyl-CoA citramalyl-CoA CoA-glutathione cyclohexa-1,4-diene-1-carbonyl-CoA cyclohexa-1,5-diene-1-carbonyl-CoA cyclohexa-2,5-diene-1-carbonyl-CoA decanoyl-CoA deoxycholoyl-CoA farnesoyl-CoA feruloyl-CoA gamma-butyrobetainyl-CoA glutaryl-CoA heptanoyl-CoA hexanoyl-CoA icosanoyl-CoA indol-3-ylacetyl-CoA isobutyryl-CoA itaconyl-CoA linoleoyl-CoA malonyl-CoA methacrylyl-CoA myristoyl-CoA N-methylanthraniloyl-CoA nonanoyl-CoA O(3)-(phosphoribosyl dephospho-CoA)-L-serine oleoyl-CoA palmitoyl-CoA pent-2-enoyl-CoA pentanoyl-CoA phenylglyoxylyl-CoA phytanoyl-CoA pimeloyl-CoA propionyl-CoA S-alkyl-CoA S-nitroso-coenzyme A sinapoyl-CoA succinyl-CoA sulfoacetyl-CoA tetracosanoyl-CoA tetradecenoyl-CoA thiophene-2-carbonyl-CoA trans-3-methylglutaconyl-CoA trans-4-carboxybut-2-enoyl-CoA trans-dec-2-enoyl-CoA trans-dodec-2-enoyl-CoA trans-feruloyl-CoA trans-hex-2-enoyl-CoA trans-oct-2-enoyl-CoA trans-tetradec-2-enoyl-CoA trans-tetradec-11-enoyl-CoA vinylacetyl-CoA Show first 5 Terms
inverse is_conjugate_base_of: coenzyme A(4-)

coenzyme A(4-) Show first 5 Terms
is_conjugate_acid_of: coenzyme A(4-)

coenzyme A(4-) Show first 5 Terms

Phenotype

Phenotype resulting from coenzyme A

Phenotype where environments contain coenzyme A

Phenotype modified by environments containing coenzyme A

Human Disease / Model Data

Citations