Search Ontology:
ChEBI

6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil

Term ID
CHEBI:149753
Synonyms
  • 2'-OH-ethyl-5-OP-U
  • 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione
  • 6-[(2-hydroxyethyl)amino]-5-[[(1E)-2-oxopropylidene]amino]-2,4(1H,3H)-pyrimidinedione
Definition
A nucleobase analogue that is uracil substituted with a (2-hydroxyethyl)amino group at position 6 and an (E)-(2-oxopropylidene)amino group at position 5; one of 20 modifications to the potent microbial riboflavin-based metabolite antigen 5-(2-oxopropylideneamino)-6-D-ribityl aminouracil (5-OP-RU), an activator of mucosal-associated invariant T (MAIT) cells when presented by the MR1 protein (reported in MED:32123373).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil
Phenotype where environments contain 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil
Phenotype modified by environments containing 6-[(2-hydroxyethyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil
Human Disease / Model Data
Citations