cenicriviroc

Term ID

CHEBI:149636

Synonyms

(5E)-8-[4-(2-butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-(4-{(S)-[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl}phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide
cenicriviroc
cenicrivirocum
CVC
TAK-652
TBR 652
TBR-652

Definition

A member of the class of benzazocines that is (5Z)-1,2,3,4-tetrahydro-1-benzazocine which is substituted by a 2-methylpropyl, N-{4-[(S)-(1-propyl-1H-imidazol-5-yl)methanesulfinyl]phenyl}carboxamide and 4-(2-butoxyethoxy)phenyl groups at positions 1, 5 and 8, respectively. It is a potent chemokine 2 and 5 receptor antagonist currently in development for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis (NASH).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether benzazocine diether imidazoles secondary carboxamide ... Show All 6 Terms

aromatic ether benzazocine diether imidazoles secondary carboxamide sulfoxide Show first 5 Terms
has_role: anti-HIV agent anti-inflammatory agent antirheumatic drug chemokine receptor 2 antagonist chemokine receptor 5 antagonist

anti-HIV agent anti-inflammatory agent antirheumatic drug chemokine receptor 2 antagonist chemokine receptor 5 antagonist Show first 5 Terms

Phenotype

Phenotype resulting from cenicriviroc

Phenotype where environments contain cenicriviroc

Phenotype modified by environments containing cenicriviroc

Human Disease Model