Search Ontology:
ChEBI
cenicriviroc
- Term ID
- CHEBI:149636
- Synonyms
-
- (5E)-8-[4-(2-butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-(4-{(S)-[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl}phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide
- cenicriviroc
- cenicrivirocum
- CVC
- TAK-652
- TBR 652
- TBR-652
- Definition
- A member of the class of benzazocines that is (5Z)-1,2,3,4-tetrahydro-1-benzazocine which is substituted by a 2-methylpropyl, N-{4-[(S)-(1-propyl-1H-imidazol-5-yl)methanesulfinyl]phenyl}carboxamide and 4-(2-butoxyethoxy)phenyl groups at positions 1, 5 and 8, respectively. It is a potent chemokine 2 and 5 receptor antagonist currently in development for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis (NASH).
- References
-
- CAS:497223-25-3
- DrugBank:DB11758
- KEGG:D09878
- PMID:16251299
- PMID:20721836
- PMID:25394040
- PMID:26247470
- PMID:26525792
- PMID:27169903
- PMID:28940700
- PMID:29448843
- PMID:29561896
- PMID:30088682
- PMID:30135687
- PMID:30179264
- PMID:30239650
- PMID:30622370
- PMID:31312356
- PMID:31629375
- PMID:31661521
- PMID:31680767
- PMID:31731005
- PMID:31881392
- PMID:31943293
- PMID:32013805
- PMID:32269742
- Wikipedia:Cenicriviroc
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from cenicriviroc
Phenotype where environments contain cenicriviroc
Phenotype modified by environments containing cenicriviroc
Human Disease / Model Data