dehydroemetine

Term ID

CHEBI:149634

Synonyms

(-)-2,3-dehydroemetine
(-)-R,S-dehydroemetine
2,3-didehydro-6',7',10,11-tetramethoxyemetan
2,3-didehydroemetine
2-dehydroemetine
6',7',10,11-tetramethoxy-2,3-didehydroemetan
BT 436
Dametin
dehidroemetina
dehydroemetine
dehydroemetinum
Mebadin
Mebadine
Ro 1-9334
Ro 1-9334/19
Ro-1-9334/19
Ro-1933419

(all 17)

Definition

A pyridoisoquinoline which was developed in response to the cardiovascular toxicity associated with emetine and results from the dehydrogenation of the heterotricylic ring of emetine. It is an antiprotozoal agent and displays antimalarial, antiamoebic, and antileishmanial properties.

References

(all 24)

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: aromatic ether isoquinolines pyridoisoquinoline

aromatic ether isoquinolines pyridoisoquinoline Show first 5 Terms
has_parent_hydride: emetan

emetan Show first 5 Terms
has_role: antileishmanial agent antimalarial antiprotozoal drug

antileishmanial agent antimalarial antiprotozoal drug Show first 5 Terms

Phenotype

Phenotype resulting from dehydroemetine

Phenotype where environments contain dehydroemetine

Phenotype modified by environments containing dehydroemetine

Phenotype affecting dehydroemetine

Human Disease Model