tilorone

Term ID

CHEBI:147347

Synonyms

• 2,7-bis[2-(diethylamino)ethoxy]-9-fluorenone
• 2,7-bis[2-(diethylamino)ethoxy]-9H-fluoren-9-one
• tilorona
• tilorone
• tiloronum

Definition

A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective α7 nicotinic acetylcholine receptor (α7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.

References

• cas:27591-97-5
• drugbank:DB17965
• hmdb:HMDB0259096
• lincs.smallmolecule:LSM-20974
• pubmed:17571857
• pubmed:18157163
• pubmed:22281189
• pubmed:23665799
• pubmed:29133569
• pubmed:29655797
• pubmed:30463695
• pubmed:30537230
• pubmed:30880776
• pubmed:32205350
• pubmed:32215760
• pubmed:33400519
• pubmed:33804032
• pubmed:34705177
• pubmed:35056541
• pubmed:37012691
• pubmed:37033868
• wikipedia.en:Tilorone

Ontology

ChEBI  ( EBI )

Resources

CTD