Search Ontology:
ChEBI
SR 144528
- Term ID
- CHEBI:146245
- Synonyms
-
- (1S-endo)-5-(4-chloro-3-methylphenyl)-1-((4-methylphenyl)methyl)-N-(1,3,3-trimethylbicyclo(2.2.1)hept-2-yl)-1H-pyrazole-3-carboxamide
- 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl]-1H-pyrazole-3-carboxamide
- 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]pyrazole-3-carboxamide
- Definition
- A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-1H-pyrazole-3-carboxylic acid with the amino group of (1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-amine. A potent and selective cannabinoid receptor type 2 (CB2 receptor) inverse agonist (Ki = 0.6 nM).
- References
-
- CAS:192703-06-3
- PMID:10400664
- PMID:10448934
- Ontology
- ChEBI ( EBI )
- has_role
- is a type of
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Phenotype
Phenotype resulting from SR 144528
| Fish | Conditions | Phenotype | Term | Figures |
|---|---|---|---|---|
| NHGRI-1 | chemical treatment: SR 144528 | Fig. 5 from Acevedo-Canabal et al., 2019 |
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Phenotype where environments contain SR 144528
| Fish | Conditions | Phenotype | Term | Figures |
|---|---|---|---|---|
| cnr2upr1/upr1 (NHGRI-1) | chemical treatment: SR 144528 | Fig. 5 from Acevedo-Canabal et al., 2019 | ||
| NHGRI-1 | chemical treatment: SR 144528 | Fig. 5 from Acevedo-Canabal et al., 2019 |
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Phenotype modified by environments containing SR 144528
No data available
Phenotype affecting SR 144528
No data available
Human Disease Model
No data available