halicin

Term ID

CHEBI:146227

Synonyms

2-amino-5-[(5-nitro-2-thiazolyl)thio]-1,3,4-thiadiazole
5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine
5-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1,3,4-thiadiazol-2-amine
5-[(5-nitro-1,3-thiazol-2-yl)thio]-1,3,4-thiadiazol-2-amine
SU 3327
SU-3327
SU3327

Definition

A member of the class of thiadiazoles that is 1,3,4-thiadiazol-2-amine which is substituted by a (5-nitro-1,3-thiazol-2-yl)sulfanediyl group at position 5. It is a c-Jun N-terminal kinase inhibitor (IC50 = 0.7uM) and exhibits antibacterial properties.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 1,3-thiazoles C-nitro compound organic sulfide primary amino compound thiadiazoles

1,3-thiazoles C-nitro compound organic sulfide primary amino compound thiadiazoles Show first 5 Terms
has_role: antibacterial agent c-Jun N-terminal kinase inhibitor

antibacterial agent c-Jun N-terminal kinase inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from halicin

Phenotype where environments contain halicin

Phenotype modified by environments containing halicin

Human Disease Model