insulin

Term ID

CHEBI:145810

Synonyms

Definition

A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the β cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies.

References

pubmed:12137720
pubmed:19251032
pubmed:25848166
pubmed:5941964
pubmed:6069707
wikipedia.en:Insulin

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from insulin

Phenotype where environments contain insulin

Phenotype modified by environments containing insulin

Phenotype affecting insulin

Human Disease Model