8-PIP-cAMP

Term ID

CHEBI:145730

Synonyms

(4aR,6R,7R,7aS)-6-[6-amino-8-(piperidin-1-yl)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide
8-piperidin-1-yladenosine 3',5'-(hydrogen phosphate)
8-piperidinoadenosine-3',5'-cyclic monophosphate

Definition

A cyclic adenyl ribonucleotide that is cAMP (cyclic adenosine 3',5'-phosphate) in which the hydrogen at position 8 has been replaced by a piperidin-1-yl group. A selective cAMP-dependent protein kinase A (PKA) activator and cAMP analogue with high selectivity for site A of PKA type I and for site B of PKA type II.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 3',5'-cyclic purine nucleotide adenyl ribonucleotide piperidines tertiary amino compound

3',5'-cyclic purine nucleotide adenyl ribonucleotide piperidines tertiary amino compound Show first 5 Terms
has_functional_parent: 3',5'-cyclic AMP

3',5'-cyclic AMP Show first 5 Terms
has_role: antineoplastic agent protein kinase A agonist

antineoplastic agent protein kinase A agonist Show first 5 Terms

Phenotype

Phenotype resulting from 8-PIP-cAMP

Phenotype where environments contain 8-PIP-cAMP

Phenotype modified by environments containing 8-PIP-cAMP

Human Disease Model