(S)-Fasnall

Term ID

CHEBI:145534

Synonyms

HS-80
N-[(3S)-1-benzylpyrrolidin-3-yl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine

Definition

An N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine in which the chiral centre has S configuration. Both enantiomers act as fatty acid synthase inhibitors, although the (S)-enantiomer was found to be more than 4 times as active as the (R)-enantiomer.

References

CAS:2138838-57-8
PMID:27265747

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine

N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine Show first 5 Terms
has_role: EC 2.3.1.85 (fatty acid synthase) inhibitor fatty acid synthesis inhibitor

EC 2.3.1.85 (fatty acid synthase) inhibitor fatty acid synthesis inhibitor Show first 5 Terms
inverse has_part: Fasnall

Fasnall Show first 5 Terms
inverse is_enantiomer_of: (R)-Fasnall

(R)-Fasnall Show first 5 Terms
is_enantiomer_of: (R)-Fasnall

(R)-Fasnall Show first 5 Terms

Phenotype

Phenotype resulting from (S)-Fasnall

Phenotype where environments contain (S)-Fasnall

Phenotype modified by environments containing (S)-Fasnall

Human Disease Model