Search Ontology:
ChEBI

CNDAC

Term ID
CHEBI:145435
Synonyms
  • 1-(2-deoxy-2-cyano-beta-D-arabinofuranosyl)cytosine
  • 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosyl-cytosine
  • 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine
  • 4-amino-1-(2-cyano-2-deoxy-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
  • DFP10917
  • TAS 109
  • TAS-109
(all 7)
Definition
A pyrimidine 2'-deoxyribonucleoside that is 2'-deoxycytidine having a cyano group in the 2'-position. It is the active metabolite of the anti-cancer drug, sapacitabine which is currently in clinical development for the treatment of hematologic malignancies and solid tumors.
References
(all 10)
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from CNDAC
Phenotype where environments contain CNDAC
Phenotype modified by environments containing CNDAC
Phenotype affecting CNDAC
Human Disease Model
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