6,7-dihydroxy-4-methylcoumarin

Term ID

CHEBI:145256

Synonyms

4-methyl-6,7-dihydroxycoumarin
4-methylaesculetin
4-methylesculetin
4-methylesculetol
6,7-dihydroxy-4-methyl-2H-1-benzopyran-2-one
6,7-dihydroxy-4-methyl-2H-benzopyran-2-one
6,7-dihydroxy-4-methyl-2H-chromen-2-one
6,7-dihydroxy-4-methylchromen-2-one
methylesculetin

Definition

A hydroxycoumarin that is 4-methylcuomarin which is substituted by hydroxy groups at positions 3 and 4. A hyaluronan synthesis inhibitor. It has also been used as a fluorescent sensor to monitor the consumption of a boronic acid in Suzuki coupling reactions; fluorescence is readily detectable by the naked eye using a standard 365 nm UV lamp.

References

cas:529-84-0
pubmed:17354230
pubmed:20380826
pubmed:21530605
pubmed:22119283
pubmed:23047850
pubmed:23485680
pubmed:23744425
pubmed:25424619
pubmed:25854527
pubmed:26071545
pubmed:2868641
pubmed:29217385
pubmed:29698774
pubmed:3004169
pubmed:3937451
pubmed:508424
pubmed:597417
pubmed:597443
pubmed:597444
pubmed:603704
pubmed:603706
pubmed:6411101
pubmed:6626341
pubmed:6626355
pubmed:7347133

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from 6,7-dihydroxy-4-methylcoumarin

Phenotype where environments contain 6,7-dihydroxy-4-methylcoumarin

Phenotype modified by environments containing 6,7-dihydroxy-4-methylcoumarin

Phenotype affecting 6,7-dihydroxy-4-methylcoumarin

Human Disease Model