PF-956980

Term ID

CHEBI:144672

Synonyms

• PF 956980
• PF-956980
• PF956980
• PFE-PKIS 8
• {(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}(pyrrolidin-1-yl)methanone

Definition

A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a methyl[(3R,4R)-4-methyl-1-(pyrrolidin-1-ylcarbonyl)piperidin-3-yl]nitrilo group. It is a potent JAK3-selective chemical probe.

References

• cas:1262832-74-5
• pdb-ccd:7GV
• pdb:5TQ6
• pubmed:18094329
• pubmed:20716767
• pubmed:23968543
• pubmed:26090665
• pubmed:27983835
• pubmed:28318222

Ontology

ChEBI  ( EBI )