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ChEBI

(2S)-2-amino-4-phosphonobutanoic acid

Term ID
CHEBI:143992
Synonyms
  • (2S)-2-amino-4-phosphonobutanoic acid
  • (2S)-2-amino-4-phosphonobutyric acid
  • (S)-2-amino-4-phosphonobutanoic acid
  • (S)-2-amino-4-phosphonobutyric acid
  • L-(+)-2-amino-4-phosphonobutanoic acid
  • L-(+)-2-amino-4-phosphonobutyric acid
  • L-AP-4
  • L-AP4
  • L-APB
Definition
A non-proteinogenc L-α-amino acid that is L-α-aminobutyric acid in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-λ5-phosphanyl group. It is a potent and selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8).
References
  • cas:23052-81-5
  • pubmed:12593528
  • pubmed:16531635
  • pubmed:1681998
  • pubmed:18598739
  • pubmed:2055241
  • pubmed:25450419
  • pubmed:29402739
  • pubmed:7525012
  • pubmed:8950003
  • pubmed:9175612
  • pubmed:9251893
  • wikipedia.en:L-AP4
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from (2S)-2-amino-4-phosphonobutanoic acid
Phenotype where environments contain (2S)-2-amino-4-phosphonobutanoic acid
Phenotype modified by environments containing (2S)-2-amino-4-phosphonobutanoic acid
Phenotype affecting (2S)-2-amino-4-phosphonobutanoic acid
Human Disease Model