(2S)-2-amino-4-phosphonobutanoic acid

Term ID

CHEBI:143992

Synonyms

(2S)-2-amino-4-phosphonobutanoic acid
(2S)-2-amino-4-phosphonobutyric acid
(S)-2-amino-4-phosphonobutanoic acid
(S)-2-amino-4-phosphonobutyric acid
L-(+)-2-amino-4-phosphonobutanoic acid
L-(+)-2-amino-4-phosphonobutyric acid
L-AP-4
L-AP4
L-APB

Definition

A non-proteinogenc L-alpha-amino acid that is L-alpha-aminobutyric acid in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-lambda(5)-phosphanyl group. It is a potent and selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: non-proteinogenic L-alpha-amino acid phosphonic acids

non-proteinogenic L-alpha-amino acid phosphonic acids Show first 5 Terms
has_role: metabotropic glutamate receptor agonist

metabotropic glutamate receptor agonist Show first 5 Terms

Phenotype

Phenotype resulting from (2S)-2-amino-4-phosphonobutanoic acid

Phenotype where environments contain (2S)-2-amino-4-phosphonobutanoic acid

Phenotype modified by environments containing (2S)-2-amino-4-phosphonobutanoic acid

Human Disease Model