Search Ontology:
ChEBI
GI254023X
- Term ID
- CHEBI:143102
- Synonyms
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- (2R)-N-[(1S)-2,2-dimethyl-1-[(methylamino)carbonyl]-propyl]-2-[(1S)-1-[formyl(hydroxy)amino]ethyl]-5-phenylpentanamide
- (2R,3S)-3-(formyl-hydroxyamino)-2-(3-phenyl-1-propyl)butanoic acid [(1S)-2,2-dimethyl-1-methylcarbamoyl-1-propyl]amide
- GI-254023X
- GI-4023
- GI4023
- N(2)-[(2R)-2-{(1S)-1-[formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide
- Definition
- A L-valine derivative that is 3-methyl-L-valine in which carboxy OH group is replaced by a methylnitrilo group and the one of the amino hydrogens is replaced by a (2R)-2-{(1S)-1-[formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl group. It is a potent MMP9 and ADAM10 metalloprotease inhibitor with IC50 of 2.5 and 5.3 nM, respectively.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from GI254023X
Phenotype where environments contain GI254023X
Phenotype modified by environments containing GI254023X
Human Disease Model