Search Ontology:
ChEBI

cinaciguat

Term ID
CHEBI:142433
Synonyms
  • 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl]amino}methyl)benzoic acid
  • BAY 58-2667
  • BAY582667
  • cinaciguat
  • cinaciguatum
Definition
A benzoic acid that is 4-(aminomethyl)benzoic acid in which the amino group is substituted by 4-carboxybutyl and 2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl groups. It is a soluble guanylate cyclase activator, used for the treatment of acute decompensated heart failure.
References
  • cas:329773-35-5
  • kegg.drug:D07577
  • patent:US2012010292
  • pdb-ccd:Z90
  • pubmed:18779378
  • pubmed:20067336
  • pubmed:20463019
  • pubmed:20730699
  • pubmed:21856817
  • pubmed:21868716
  • pubmed:22474005
  • pubmed:22713287
  • pubmed:23144773
  • pubmed:24090476
  • pubmed:25200007
  • pubmed:26520063
  • pubmed:27122537
  • pubmed:27853261
  • pubmed:28894114
  • pubmed:29138269
  • pubmed:29653192
  • reaxys:9676935
  • wikipedia.en:Cinaciguat
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from cinaciguat
Phenotype where environments contain cinaciguat
Phenotype modified by environments containing cinaciguat
Phenotype affecting cinaciguat
Human Disease Model