Search Ontology:
ChEBI
vericiguat
- Term ID
- CHEBI:142432
- Synonyms
-
- BAY-1021189
- BAY1021189
- methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate
- methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate
- MK-1242
- vericiguat
- vericiguatum
- Definition
- A pyrazolopyridine that is 5-fluoro-1H-pyrazolo[3,4-b]pyridine in which the amino hydrogen at position 1 has been substituted by a 2-fluorobenzyl group and the hydrogen at position 3 has been substituted by a 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl group. It is a soluble guanylate cyclase stimulator which is used for treatment of chronic heart failure.
- References
-
- CAS:1350653-20-1
- KEGG:D11051
- PMCID:PMC4565100
- PMID:24092345
- PMID:25056511
- PMID:25737289
- PMID:26547357
- PMID:28369340
- PMID:28557445
- PMID:29032136
- Patent:US2012022084
- Reaxys:22098890
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from vericiguat
Phenotype where environments contain vericiguat
Phenotype modified by environments containing vericiguat
Human Disease Model