lificiguat

Term ID

CHEBI:142430

Synonyms

• 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole
• 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole
• [5-(1-benzyl-1H-indazol-3-yl)-2-furyl]methanol
• lificiguat
• lificiguatum
• YC-1

Definition

A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.

References

• cas:170632-47-0
• pubmed:10369473
• pubmed:11687640
• pubmed:20513359
• pubmed:21665942
• pubmed:24265542
• pubmed:27498367
• pubmed:27938560
• pubmed:28978999
• pubmed:28983668
• pubmed:29156788
• pubmed:29441848
• pubmed:29512783
• pubmed:30250592
• pubmed:7527671
• pubmed:9059849
• pubmed:9443939
• reaxys:8006642

Ontology

ChEBI  ( EBI )