Search Ontology:
ChEBI

(2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine

Term ID
CHEBI:142183
Synonyms
  • (1S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine
  • (2S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
  • (S)-2-(6-chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine
  • (S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine
  • (S)-6-chloro-5-fluoro-alpha-methyl-1H-indole-1-ethanamine
  • ORG 35030
  • Ro 60-0175
  • Ro-60-0175
  • Ro60-0175
Definition
A 1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine that has S configuration. A selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt.
References
  • lincs.smallmolecule:LSM-1601
  • patent:EP655440
  • pubmed:10219979
  • pubmed:10498829
  • pubmed:10814735
  • pubmed:10903970
  • pubmed:11105935
  • pubmed:11399662
  • pubmed:12604698
  • pubmed:14666118
  • pubmed:17473916
  • pubmed:17653111
  • pubmed:22342986
  • pubmed:23201361
  • pubmed:23535834
  • pubmed:28583411
  • pubmed:9225301
  • pubmed:9694950
  • reaxys:7795121
  • wikipedia.en:Ro60-0175
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine
Phenotype where environments contain (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine
Phenotype modified by environments containing (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine
Phenotype affecting (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine
Human Disease Model