delanzomib

Term ID

CHEBI:141530

Synonyms

• [(1R)-1-[[(2S,3R)-3-hydroxy-1-oxo-2-[[oxo-(6-phenyl-2-pyridyl)methyl]amino]butyl]amino]-3-methylbutyl]boronic acid
• [(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridin-2-yl)carbonylamino]butanoyl]amino]-3-methyl-butyl]boronic acid
• [(1R)-3-methyl-1-({N-[(6-phenylpyridin-2-yl)carbonyl]-L-threonyl}amino)butyl]boronic acid
• boronic acid, ((1R)-1-(((2S,3R)-3-hydroxy-1-oxo-2-(((6-phenyl-2-pyridinyl)carbonyl)amino)butyl)amino)-3-methylbutyl)-
• CEP-18770
• CT-47098
• delanzomib
• delanzomibum

Definition

A C-terminal boronic acid peptide inhibitor which induces apoptosis in multiple myeloma, hematological and solid tumor cell lines.

References

• cas:847499-27-8
• drugbank:DB11956
• kegg.drug:D10110
• patent:WO2011087822
• pubmed:18057228
• pubmed:19958357
• pubmed:20872901
• pubmed:22178195
• pubmed:22906694
• pubmed:23058787
• pubmed:28140719
• pubmed:29371974
• pubmed:29848702
• reaxys:12211043

Ontology

ChEBI  ( EBI )