fazarabine

Term ID

CHEBI:141077

Synonyms

1-beta-D-Arabinofuranosyl-5-azacytosine
4-amino-1-beta-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one
4-Amino-1-beta-D-arabinofuranosyl-s-triazin-2(1H)-one
5-azacytarabine
5-azacytosine arabinoside
Ara-AC
fazarabina
fazarabine
fazarabinum

Definition

An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-arabinofuranosyl residue via an N-glycosidic linkage. A synthetic analogue of cytosine arabinoside and 5-azacytidine that incorporates structural features of both compounds, it shows good activity against a variety of transplanted tumors.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-glycosyl-1,3,5-triazine nucleoside analogue

N-glycosyl-1,3,5-triazine nucleoside analogue Show first 5 Terms
has_functional_parent: beta-D-arabinofuranose

beta-D-arabinofuranose Show first 5 Terms
has_role: antineoplastic agent

antineoplastic agent Show first 5 Terms

Phenotype

Phenotype resulting from fazarabine

Phenotype where environments contain fazarabine

Phenotype modified by environments containing fazarabine

Human Disease / Model Data

Citations