GANT61

Term ID

CHEBI:140908

Synonyms

2-({3-[2-(dimethylamino)benzyl]-2-(pyridin-4-yl)tetrahydropyrimidin-1(2H)-yl}methyl)-N,N-dimethylaniline
GANT-61
NSC 136476

Definition

An aminal that is hexahydropyrimidine which is substituted on each nitrogen by a 2-(dimethylamino)benzyl group, and at the aminal carbon by a pyridin-4-yl group. A Hedgehog signaling pathway and Gli protein inhibitor.

References

pubmed:20488474
pubmed:22265815
pubmed:22398221
pubmed:23200667
pubmed:24521409
pubmed:24694609
pubmed:24962990
pubmed:25064451
pubmed:25323222
pubmed:25432075
pubmed:25544756
pubmed:26843616
pubmed:27275540
pubmed:27349387
pubmed:27572939
pubmed:27601167
pubmed:27662839
pubmed:27713179
pubmed:27793816
pubmed:27863397
pubmed:27894350
pubmed:28109323
pubmed:28123507
pubmed:28144905
pubmed:28208838
pubmed:28211214
pubmed:28446294
pubmed:28457748
pubmed:28870808
pubmed:28965853
pubmed:29231999
pubmed:29250185
pubmed:29328464
pubmed:29329585
pubmed:29338454
pubmed:29581853
pubmed:29642386
pubmed:29702195

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from GANT61

Phenotype where environments contain GANT61

Phenotype modified by environments containing GANT61

Phenotype affecting GANT61

Human Disease Model