Search Ontology:
ChEBI
GSK1016790A
- Term ID
- CHEBI:140524
- Synonyms
-
- GSK 1016790A
- GSK-1016790A
- N-[(2S)-1-(4-{N-[(2,4-dichlorophenyl)sulfonyl]-L-seryl}piperazin-1-yl)-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
- N-[(2S)-1-{4-[(2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
- Definition
- A tertiary carboxamide that is piperazine in which one of the amino groups has undergone condensation with the carboxy group of N-[(2,4-dichlorophenyl)sulfonyl]-L-serine, while the other has undergone condensation with the carboxy group of N-(1-benzothiophen-2-ylcarbonyl)-L-leucine. It is a cell-permeable, potent and selective agonist of the TRPV4 (transient receptor potential vanilloid 4) channel.
- References
-
- pubmed:18499743
- pubmed:21339821
- pubmed:22689561
- pubmed:24186096
- pubmed:25150065
- pubmed:26991376
- pubmed:27616980
- pubmed:27799895
- pubmed:28359774
- pubmed:28663724
- pubmed:28794166
- pubmed:29293584
- pubmed:29439248
- pubmed:29569183
- reaxys:12914325
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from GSK1016790A
Phenotype where environments contain GSK1016790A
Phenotype modified by environments containing GSK1016790A
Phenotype affecting GSK1016790A
Human Disease Model