MC1568

Term ID

CHEBI:140475

Synonyms

• 3-{5-[3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxyacrylamide
• MC-1568

Definition

A hydroxamic acid that is N-methylpyrrole which is substituted at positions 2 and 5 by 3-(hydroxyamino)-3-oxoprop-1-en-1-yl and 3-(m-fluorophenyl)-3-oxoprop-1-en-1-yl groups, respectively. It is a potent and selective inhibitor of class II (IIa) histone deacetylase (HDAC II).

References

• cas:852475-26-4
• pubmed:15857140
• pubmed:23176534
• pubmed:24450497
• pubmed:27103167
• pubmed:27660204
• pubmed:27739328
• pubmed:28732762
• pubmed:29401190
• pubmed:29412739
• pubmed:29482060
• reaxys:26700969

Ontology

ChEBI  ( EBI )