Search Ontology:
ChEBI

ANA-12

Term ID
CHEBI:140465
Synonyms
  • ANA12
  • N-{2-[(2-oxoazepan-3-yl)carbamoyl]phenyl}-1-benzothiophene-2-carboxamide
Definition
A secondary carboxamide that is anthranilic acid in which the carboxy group has undergone condensation with the primary amino group of α-amino-ε-caprolactam, while the aryl-amino group has undergone condensation with the carboxy group of 1-benzothiophene-2-carboxylic acid. It is a selective, non-competitive antagonist of tropomyosin receptor kinase B (TrkB, also known as tyrosine receptor kinase B).
References
  • cas:219766-25-3
  • pubmed:26337614
  • pubmed:26452067
  • pubmed:28705440
  • pubmed:29294331
  • pubmed:30097625
  • reaxys:29788980
  • wikipedia.en:ANA-12
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from ANA-12
Phenotype where environments contain ANA-12
Phenotype modified by environments containing ANA-12
Phenotype affecting ANA-12
Human Disease Model