eribaxaban

Term ID

CHEBI:140420

Synonyms

• (2R,4R)-N(1)-(4-chlorophenyl)-N(2)-[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]-4-methoxypyrrolidine-1,2-dicarboxamide
• eribaxaban
• eribaxabanum
• PD 0348292
• PD 348,292
• PD 348292
• PD-0348292
• PD0348292

Definition

A member of the class of pyrrolidines that is (2R,4R)-N¹-(p-chlorophenyl)-4-methoxypyrrolidine-1,2-dicarboxamide in which the nitrogen of the 2-carbamoyl group has been substituted by a 2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl group. It is a synthetic organic anticoagulant compound that targets activated factor Xa in the coagulation cascade.

References

• cas:536748-46-6
• drugbank:DB06920
• kegg.drug:D08913
• pdb-ccd:230
• pubmed:17683371
• pubmed:18096830
• pubmed:18392334
• pubmed:19071881
• pubmed:23782955
• pubmed:26861270
• pubmed:27119575
• pubmed:28793291
• reaxys:12467251

Ontology

ChEBI  ( EBI )