Search Ontology:
ChEBI
cefiderocol
- Term ID
- CHEBI:140376
- Synonyms
-
- (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-({1-[2-(2-chloro-3,4-dihydroxybenzamido)ethyl]pyrrolidinium-1-yl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- cefiderocol
- cefiderocolum
- GSK 2696266
- GSK-2696266
- GSK2696266
- RSC 649266
- S 649266
- S-649266
- S649266
- Definition
- A fourth-generation siderophore cephalosporin antibiotic having {1-[2-(2-chloro-3,4-dihydroxybenzamido)ethyl]pyrrolidinium-1-yl}methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino side groups located at positions 3 and 7 respectively, developed to combat a variety of bacterial pathogens, including β-lactam- and carbapenem-resistant organisms.
- References
-
- cas:1225208-94-5
- chemspider:52084902
- drugbank:DB14879
- drugcentral:5352
- kegg.drug:D11302
- patent:EP2341053
- pmc:PMC6253113
- pmc:PMC7776597
- pmc:PMC7777002
- pubmed:27139465
- pubmed:28369471
- pubmed:28748397
- pubmed:28848004
- pubmed:29017833
- pubmed:29061741
- pubmed:29111435
- pubmed:29311072
- pubmed:29318906
- pubmed:29471305
- pubmed:29960205
- pubmed:30323050
- pubmed:30730562
- pubmed:32522005
- pubmed:32727829
- pubmed:33068441
- pubmed:33164837
- pubmed:33199383
- pubmed:33313656
- pubmed:33393598
- pubmed:33532823
- pubmed:33573148
- pubmed:33670891
- pubmed:33677539
- pubmed:33849355
- pubmed:33894839
- pubmed:33915286
- reaxys:21605074
- wikipedia.en:Cefiderocol
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from cefiderocol
Phenotype where environments contain cefiderocol
Phenotype modified by environments containing cefiderocol
Phenotype affecting cefiderocol
Human Disease Model