cyclosporin A metabolite M26

Term ID

CHEBI:140177

Synonyms

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(2R,3R)-5-(2-hydroxyethyl)-3-methyltetrahydrofuran-2-yl]-9-(2-hydroxy-2-methylpropyl)-6,18,24-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclot
AM1c9
cyclosporin A metabolite AM1c9
cyclosporin metabolite AM1c9
cyclosporin metabolite M26
cyclosporine A metabolite AM1c9
cyclosporine A metabolite M26
cyclosporine metabolite AM1c9
cyclosporine metabolite M26
M26

Definition

A cyclosporin A derivative that is cyclosporin A in which residue 9 (N-methylleucine) has been hydroxylated at the carbon bearing the two methyl groups and in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has been hydroxylated at position 8 while the hydroxy group at position 3 has undergone addition to the double bond to give the corresponding oxolane.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclosporin A derivative oxolanes tertiary alcohol

cyclosporin A derivative oxolanes tertiary alcohol Show first 5 Terms
has_functional_parent: cyclosporin A metabolite M8

cyclosporin A metabolite M8 Show first 5 Terms
has_role: drug metabolite

drug metabolite Show first 5 Terms

Phenotype

Phenotype resulting from cyclosporin A metabolite M26

Phenotype where environments contain cyclosporin A metabolite M26

Phenotype modified by environments containing cyclosporin A metabolite M26

Human Disease Model