cyclosporin A metabolite M17

Term ID

CHEBI:140154

Synonyms

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1,6-dihydroxy-2-methylhex-4-en-1-yl]-30-ethyl-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23
6-[(2S,3R,4R,6E)-3,8-dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin
AM1
CsA M17
cyclosporin metabolite AM1
cyclosporin metabolite M17
cyclosporine A metabolite M17
cyclosporine metabolite M17
M17
OL 17
OL-17

Definition

A cyclosporin A derivative that is cyclosporin A in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has undergone allylic oxidation to give the corresponding primary allylic alcohol. It specifically inhibits growth of renal cells in culture.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: cyclosporin A derivative primary allylic alcohol

cyclosporin A derivative primary allylic alcohol Show first 5 Terms
has_role: drug metabolite

drug metabolite Show first 5 Terms
inverse has_functional_parent: cyclosporin A metabolite M1A cyclosporin A metabolite M8 cyclosporin A metabolite M18 cyclosporin A metabolite M25

cyclosporin A metabolite M1A cyclosporin A metabolite M8 cyclosporin A metabolite M18 cyclosporin A metabolite M25 Show first 5 Terms

Phenotype

Phenotype resulting from cyclosporin A metabolite M17

Phenotype where environments contain cyclosporin A metabolite M17

Phenotype modified by environments containing cyclosporin A metabolite M17

Human Disease Model