cyclosporin A metabolite M1

Term ID

CHEBI:140152

Synonyms

(3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-ethyl-33-((E,1R,2R)-1-hydroxy-2-methyl-hex-4-enyl)-9-(2-hydroxy-2-methyl-propyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,18,24-tris(2-methylpropyl)-3,21-dipropan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacon
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-9-(2-hydroxy-2-methylpropyl)-6,18,24-triisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane
(4-hydroxy-N-methyl-L-leucine)cyclosporine
(gamma-OH)MeLeu-9-cyclosporin
(gamma-OH)MeLeu-9-cyclosporine
AM9
cyclosporin metabolite AM9
cyclosporine metabolite AM9
cyclosporine metabolite M1

Definition

A cyclosporin A derivative that is cyclosporin A in which residue 9 (N-methylleucine) has undergone oxidation so a to introduce a hydroxy group at the carbon bearing the two methyl groups.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: cyclosporin A derivative tertiary alcohol

cyclosporin A derivative tertiary alcohol Show first 5 Terms
has_role: drug metabolite

drug metabolite Show first 5 Terms
inverse has_functional_parent: cyclosporin A metabolite M8 cyclosporin A metabolite M10 cyclosporin A metabolite M13 cyclosporin A metabolite M16

cyclosporin A metabolite M8 cyclosporin A metabolite M10 cyclosporin A metabolite M13 cyclosporin A metabolite M16 Show first 5 Terms

Phenotype

Phenotype resulting from cyclosporin A metabolite M1

Phenotype where environments contain cyclosporin A metabolite M1

Phenotype modified by environments containing cyclosporin A metabolite M1

Human Disease Model