Search Ontology:
ChEBI

sepantronium bromide

Term ID
CHEBI:139608
Synonyms
  • 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide
  • 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide
  • bromure de sepantronium
  • bromuro de sepantronio
  • sepantronii bromidum
  • sepantronium bromide
  • YM 155
  • YM-155
Definition
An organic bromide salt consisting of sepantronium cations and bromide anions. It has been found to selectively inhibit survivin (BIRC5) gene promoter activity and to down-regulate survivin in vitro, so leading to induction of apoptosis.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from sepantronium bromide
Phenotype where environments contain sepantronium bromide
Phenotype modified by environments containing sepantronium bromide
Human Disease Model
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