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ChEBI

golgicide A

Term ID
CHEBI:139037
Synonyms
Definition
A diastereoisomeric mixture comprising racemic cis- and racemic trans-goglioside A in a 10:1 ratio. It is a potent and rapidly reversible GBF1 (Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1) inhibitor. The (3aS,4R,9bR) isomer is the most active (see Bioorg. Med. Chem. Lett., 2012, 22, 5177-5181).
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from golgicide A
Phenotype where environments contain golgicide A
Phenotype modified by environments containing golgicide A
Phenotype affecting golgicide A
Human Disease Model