prinomastat

Term ID

CHEBI:138885

Synonyms

(3S)-N-hydroxy-2,2-dimethyl-4-{[4-(pyridin-4-yloxy)phenyl]sulfonyl}thiomorpholine-3-carboxamide
(S)-2,2-dimethyl-4-{[p-(4-pyridyloxy)phenyl]sulfonyl}-3-thiomorpholinecarbohydroxamic acid
AG 3340
AG-3340
AG3340
prinomastat
prinomastatum

Definition

A hydroxamic acid that is (3S)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide in which the hydrogen attached to the thiomorpholine nitrogen has been replaced by a [4-(pyridin-4-yloxy)phenyl]sulfonyl group. It is a selective inhibitor with of matrix metalloproteinases (MMPs) 2, 3, 9, 13, and 14.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether hydroxamic acid pyridines sulfonamide thiomorpholines

aromatic ether hydroxamic acid pyridines sulfonamide thiomorpholines Show first 5 Terms
has_role: antineoplastic agent EC 3.4.24.35 (gelatinase B) inhibitor matrix metalloproteinase inhibitor

antineoplastic agent EC 3.4.24.35 (gelatinase B) inhibitor matrix metalloproteinase inhibitor Show first 5 Terms
inverse is_conjugate_acid_of: prinomastat(1+)

prinomastat(1+) Show first 5 Terms
is_conjugate_base_of: prinomastat(1+)

prinomastat(1+) Show first 5 Terms

Phenotype

Phenotype resulting from prinomastat

Phenotype where environments contain prinomastat

Phenotype modified by environments containing prinomastat

Human Disease Model