protectin D1

Term ID

CHEBI:138655

Synonyms

(4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid
(4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxydocosahexaenoic acid
(N)PD1
(neuro)protectin D1
10(R),17(S)-dihydroxydocosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid
neuroprotectin D1
NPD1
PD1

Definition

A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13E,15Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10R,17S-stereoisomer). Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: dihydroxydocosahexaenoic acid protectin secondary allylic alcohol

dihydroxydocosahexaenoic acid protectin secondary allylic alcohol Show first 5 Terms
has_role: anti-inflammatory agent apoptosis inhibitor hepatoprotective agent human xenobiotic metabolite neuroprotective agent ... Show All 7 Terms

anti-inflammatory agent apoptosis inhibitor hepatoprotective agent human xenobiotic metabolite neuroprotective agent PPARgamma agonist specialised pro-resolving mediator Show first 5 Terms
inverse has_functional_parent: 22-hydroxyprotectin D1

22-hydroxyprotectin D1 Show first 5 Terms
inverse is_conjugate_base_of: protectin D1(1-)

protectin D1(1-) Show first 5 Terms
is_conjugate_acid_of: protectin D1(1-)

protectin D1(1-) Show first 5 Terms

Phenotype

Phenotype resulting from protectin D1

Phenotype where environments contain protectin D1

Phenotype modified by environments containing protectin D1

Human Disease Model