(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid

Term ID

CHEBI:138653

Synonyms

(10S,17S)-DiHDHA
(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid
10(S),17(S)-DiHDHA
10(S),17(S)-dihydroxydocosa-4Z,7Z,11E,13Z,15E,19Z-hexaenoic acid
10S,17S-diHDHA
10S,17S-DiHDoHE
10S,17S-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid
PDX
protectin DX

Definition

A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13Z,15E,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10S,17S-stereoisomer). A natural isomer of protectin D1, one of the specialised proresolving mediators.

References

lipidmaps:LMFA04040003
pubmed:16424216
pubmed:20833872
pubmed:24262603
pubmed:26650044
pubmed:30586310
pubmed:33835594
pubmed:40235172
reaxys:19424117

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from (4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid

Phenotype where environments contain (4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid

Phenotype modified by environments containing (4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid

Phenotype affecting (4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosahexaenoic acid

Human Disease Model