Search Ontology:
ChEBI
isoprostane
- Term ID
- CHEBI:138408
- Synonyms
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- isoprostanes
- IsoPs
- Definition
- Any icosanoid with a prostaglandin-like structure formed in vivo by non-enzymatic free radical-catalysed reactions involving peroxidation of essential fatty acids (mainly arachidonic acid but also other fatty acids with 3 or more double bonds). Isoprostanes are abundant in tissues and fluids and have immunomodulating activity. Their concentration is dependent on the amount of oxidative stress and may be upregulated in certain diseases such as cancer, cardiovascular and neurological disorders.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has subtype
-
Show first 5 Terms
Phenotype
Phenotype resulting from isoprostane
Phenotype where environments contain isoprostane
Phenotype modified by environments containing isoprostane
Human Disease Model