nocamycin I

Term ID

CHEBI:138066

Synonyms

(-)-nocamycin I
Antibiotic BU 2313B
BU 2313B
Bu-2313B
methyl (1S,2S,3R,5S,8S,9R,10R)-10-[(2R,3E,5E,7E)-7-(2,4-dioxopyrrolidin-3-ylidene)-7-hydroxy-4-methylhepta-3,5-dien-2-yl]-3,5,9-trimethyl-7-oxo-4,11,12-trioxatricyclo[6.3.1.0(1,5)]dodecane-2-carboxylate
methyl (2R,3S,3aS,5R,6R,7S,9aS)-5-[(2R,3E,5E,7E)-7-(2,4-dioxopyrrolidin-3-ylidene)-7-hydroxy-4-methylhepta-3,5-dien-2-yl]-2,6,9a-trimethyl-8-oxooctahydro-3a,7-epoxyfuro[3,2-b]oxocine-3-carboxylate

Definition

An organic heterotricyclic compound and tetramic acid derivative originally isolated from an unidentified oligosporic actinomycete strain (no. E864-861) and found to be active against both Gram-positive and Gram-negative anaerobic bacteria as well as some aerobic bacteria such as Streptococci. The methyl ester of nocamycin E.

References

MetaCyc:CPD-18224
PMID:28818448
PMID:6920296
Patent:US4181574

Ontology

ChEBI ( EBI )

Relationships

is a type of: enol gamma-lactam methyl ester olefinic compound organic heterotricyclic compound ... Show All 7 Terms

enol gamma-lactam methyl ester olefinic compound organic heterotricyclic compound spiroketal tetramic acids Show first 5 Terms
has_functional_parent: nocamycin E

nocamycin E Show first 5 Terms
has_role: antibacterial agent bacterial metabolite

antibacterial agent bacterial metabolite Show first 5 Terms
inverse is_conjugate_base_of: nocamycin I(1-)

nocamycin I(1-) Show first 5 Terms
is_conjugate_acid_of: nocamycin I(1-)

nocamycin I(1-) Show first 5 Terms

Phenotype

Phenotype resulting from nocamycin I

Phenotype where environments contain nocamycin I

Phenotype modified by environments containing nocamycin I

Human Disease Model