ilomastat

Term ID

CHEBI:137236

Synonyms

• (2R)-N(4)-hydroxy-N(1)-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide
• CS 610
• galardin
• GM 6001
• GM-6001
• GM6001
• ilomastat

Definition

An N-acyl-amino acid obtained by formal condensation of the carboxy group of (2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoic acid with the amino group of N-methyl-L-tryptophanamide. A cell permeable broad-spectrum matrix metalloproteinase (MMP) inhibitor

References

• cas:142880-36-2
• kegg.drug:D03793
• lincs.smallmolecule:LSM-3143
• pdb-ccd:GM6
• pubmed:12410973
• pubmed:14568001
• pubmed:15350544
• pubmed:16565079
• pubmed:16712832
• pubmed:18782669
• pubmed:18790756
• pubmed:18837084
• pubmed:19545667
• pubmed:20299089
• pubmed:20818082
• pubmed:21040999
• pubmed:21146503
• pubmed:22512086
• pubmed:22903888
• pubmed:23141517
• pubmed:23870824
• pubmed:24380772
• pubmed:24589605
• pubmed:25576979
• pubmed:26171681
• pubmed:26394037
• pubmed:27038494
• pubmed:27112177
• pubmed:27296149
• pubmed:27708133
• pubmed:27743382
• pubmed:28297575
• pubmed:28298987
• pubmed:28417261
• reaxys:7982373
• wikipedia.en:Ilomastat

Ontology

ChEBI  ( EBI )

Resources

CTD