taltirelin

Term ID

CHEBI:135653

Synonyms

1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide
N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide
TA 0910
TA-0910
taltirelin
taltirelin hydrate
taltirelina
taltireline
taltirelinum

(all 9)

Definition

An oligopeptide comprising of (4S)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid, L-histidine and L-prolinamide joined in sequence by peptide linkages. It is a thyrotropin-releasing hormone (TRH) analog. Its tetrahydrate form is approved in Japan for the treatment of spinal muscular atrophy.

References

(all 25)

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: oligopeptide

oligopeptide Show first 5 Terms
has_role: analgesic neuroprotective agent nootropic agent

analgesic neuroprotective agent nootropic agent Show first 5 Terms
inverse has_part: taltirelin tetrahydrate

taltirelin tetrahydrate Show first 5 Terms

Phenotype

Phenotype resulting from taltirelin

Phenotype where environments contain taltirelin

Phenotype modified by environments containing taltirelin

Phenotype affecting taltirelin

Human Disease Model