Search Ontology:
ChEBI

camostat

Term ID
CHEBI:135632
Synonyms
  • 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
  • 4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
  • camostat
  • camostat mesilate
  • camostatum
  • N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate
Definition
A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
inverse is_conjugate_acid_of
is_conjugate_base_of
Phenotype
Phenotype resulting from camostat
Phenotype where environments contain camostat
Phenotype modified by environments containing camostat
Human Disease / Model Data
Citations
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