crisaborole

Term ID

CHEBI:134677

Synonyms

• 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile
• AN 2728
• AN-2728
• AN2728
• crisaborole
• Crisaborole topical ointment 2%
• Eucrisa

Definition

A member of the class of benzoxaboroles that is 5-hydroxy-1,3-dihydro-2,1-benzoxaborole in which the phenolic hydrogen has been replaced by a 4-cyanophenyl group. A phosphodiesterase 4 inhibitor that is used for treatment of mild to moderate atopic dermatitis in children and adults.

References

• cas:906673-24-3
• kegg.drug:D10873
• pubmed:19303290
• pubmed:19876791
• pubmed:20094643
• pubmed:20383346
• pubmed:23625818
• pubmed:24852768
• pubmed:26461821
• pubmed:26659931
• pubmed:26777394
• pubmed:26885784
• pubmed:27050693
• pubmed:27193740
• pubmed:27283509
• pubmed:27335049
• pubmed:27353073
• pubmed:27417017
• pubmed:27525671
• pubmed:27928191
• pubmed:28163553
• reaxys:11622826

Ontology

ChEBI  ( EBI )