Search Ontology:
ChEBI
MI-63
- Term ID
- CHEBI:134602
- Synonyms
-
- (2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-[2-(morpholin-4-yl)ethyl]-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide
- Definition
- An azaspiro compound resulting from the formal fusion of position 3 of 6-chloro-oxindole with position 3 of (2R,3SS5S)-3-(3-chloro-2-fluorophenyl)-5-(2,2-dimethylpropyl)-N-[2-(morpholin-4-yl)ethyl]pyrrolidine-2-carboxamide. It is a potent inhibitor of the MDM2-p53 interaction.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 7 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from MI-63
Phenotype where environments contain MI-63
Phenotype modified by environments containing MI-63
Human Disease Model