doxorubicinol

Term ID

CHEBI:133817

Synonyms

(1S,3S)-3-[(1S)-1,2-dihydroxyethyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
13-dihydrodoxorubicin
adriamycinol
Antibiotic 27706RP
DOXOL

Definition

A member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties.

References

cas:54193-28-1
hmdb:HMDB0041884
pubmed:10408701
pubmed:11448472
pubmed:12647011
pubmed:16168722
pubmed:1628370
pubmed:16614166
pubmed:16915573
pubmed:16958789
pubmed:17197005
pubmed:17379584
pubmed:18371724
pubmed:18967867
pubmed:19174209
pubmed:23192654
pubmed:23337906
pubmed:24631816
pubmed:25446851
pubmed:27447545
pubmed:2897122
pubmed:8298821
pubmed:8595168
pubmed:9261889
pubmed:9696578
pubmed:9888978
reaxys:6773847

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from doxorubicinol

Phenotype where environments contain doxorubicinol

Phenotype modified by environments containing doxorubicinol

Phenotype affecting doxorubicinol

Human Disease Model