Search Ontology:
ChEBI
venetoclax
- Term ID
- CHEBI:133021
- Synonyms
-
- 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro-4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide
- ABT 199
- ABT-199
- ABT199
- GDC 0199
- Venclexta
- venetoclax
- Definition
- A member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion.
- References
-
- CAS:1257044-40-8
- Drug_Central:5133
- KEGG:D10679
- PMID:24794804
- PMID:25185206
- PMID:25658896
- PMID:25768998
- PMID:25829398
- PMID:25882699
- PMID:25957396
- PMID:26110568
- PMID:26467384
- PMID:26493374
- PMID:26516589
- PMID:26565405
- PMID:26589495
- PMID:26711339
- PMID:26927160
- PMID:26967820
- PMID:27030982
- PMID:27056887
- PMID:27092880
- PMID:27095788
- PMID:27103402
- PMID:27166183
- PMID:27283158
- PMID:27466751
- PMID:27480872
- Reaxys:20908256
- Wikipedia:Venetoclax
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from venetoclax
Phenotype where environments contain venetoclax
Phenotype modified by environments containing venetoclax
Human Disease Model