5-aminolevulinic acid hydrochloride

Term ID

CHEBI:132969

Synonyms

4-carboxy-2-oxobutan-1-aminium chloride
5-amino-4-oxopentanoic acid hydrochloride
5-aminolevulinic acid.HCl
AMELUZ
Aminolevulinic acid hydrochloride
delta-Aminolevulinic acid hydrochloride
Levulan
Levulan Kerastick

Definition

A hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

References

cas:5451-09-2
drugbank:DB00855
kegg.drug:D02908
pubmed:26886586
pubmed:27012885
pubmed:27052440
pubmed:27059226
pubmed:27106399
pubmed:27127156
pubmed:27142575
pubmed:27150264
pubmed:27178236
pubmed:27183272
pubmed:27235981
pubmed:27238205
pubmed:27239432
pubmed:27272080
pubmed:27283485
pubmed:27329428
pubmed:27354630
pubmed:27374931
pubmed:27375183
pubmed:27378246
pubmed:27421917
pubmed:27472495
pubmed:27489425
pubmed:27496021
reaxys:3690651
wikipedia.en:Aminolevulinic_acid

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from 5-aminolevulinic acid hydrochloride

Phenotype where environments contain 5-aminolevulinic acid hydrochloride

Phenotype modified by environments containing 5-aminolevulinic acid hydrochloride

Phenotype affecting 5-aminolevulinic acid hydrochloride

Human Disease Model