NAV2729

Term ID

CHEBI:132811

Synonyms

2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-4H-pyrazolo[1,5-a]pyrimidin-7-one
2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
NAV-2729

Definition

A pyrazolopyrimidine that is 4H-pyrazolo[1,5-a]pyrimidin-7-one which is substituted at positions 2, 3, and 5 by benzyl, p-chlorophenyl, and p-nitrophenyl groups, respectively. It is an inhibitor of ADP-ribosylation factor 6 (ARF6), a member of the ADP ribosylation factor family of GTP-binding proteins.

References

PMID:27265506
Patent:WO2015183989
Reaxys:24485055

Ontology

ChEBI ( EBI )

Relationships

is a type of: C-nitro compound monochlorobenzenes pyrazolopyrimidine

C-nitro compound monochlorobenzenes pyrazolopyrimidine Show first 5 Terms
has_role: inhibitor

inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from NAV2729

Phenotype where environments contain NAV2729

Phenotype modified by environments containing NAV2729

Human Disease / Model Data

Citations